Joint conference of the
3rd Annual HPSG meeting and the 9th ALPD symposium
21-23 NOVEMBER 2014, Novotel Hotel SZEGED
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Programme:
21 NOVEMBER 2014 (Friday)
8:00 – 9:00 Breakfast meeting with the International guests
István Vedres Meeting Room
Moderator: Péter Hegyi (Szeged, Hungary)
Brain storming – by invitation only
9:30 – 10:00 Opening of the 3rd HPSG meeting
Lajos Tisza Meeting Room
Chairs:Péter Hegyi (Szeged, Hungary), Miklós Sahin-Tóth (Boston, USA),
István Hritz (Budapest, Hungary)
Sponsors: Sager Pharma – Abbott – Berlin Chemie – Szekerke Mária RA
9:30 – 9:40 Welcome Notes by the sponsors
9:40 –10:00 Péter Hegyi (Szeged, Hungary)
HPSG: History and Future perspectives
10:00 – 12:10 Focus on Pediatric Pancreatitis
Lajos Tisza Meeting Room
Chairs:Gábor Veres (Budapest, Hungary), Csaba Bereczki (Szeged, Hungary), Natália Lásztity (Budapest, Hungary)
Session introduction by Péter Hegyi (Szeged, Hungary)
10:00 – 10:30 Maisam Abu-El-Haija (Cincinnati, USA)
AP in Children
10:30 – 10:40 Aliye Uc (Iowa, USA)
Introduction of INSPPIRE
10:40 – 11:10 Aliye Uc (Iowa, USA)
ARP and CP in Children
11:10 – 11:40 Mark Lowe (Pittsburgh, USA)
Treatment of ARP and CP with a focus on TP-IAT
11:40 – 12:10 Heiko Witt (Münich, Germany)
Genetic mutations in pediatric CP patients in Germany.
12:50 – 13:20 Data Administration (lunch session)
Lajos Tisza Meeting Room
Chair:Andrea Szentesi OPR Director (Szeged, Hungary)
12:50 – 13.20 Andrea Szentesi OPR Director (Szeged, Hungary)
Technical guideline for the web based data registry
13:30 – 15:30 Pancreas Genetic Testing
Lajos Tisza Meeting Room
Chairs:Márta Széll (Szeged, Hungary), Balázs Németh (Szeged, Hungary)
Session introduction by Miklós Sahin-Tóth (Boston, USA)
13:30 – 14:00 David C. Whitcomb (Pittsburgh, USA)
Genetics of pancreatitis with a focus on pancreatic ducts.
14:00 – 14:30 Miklós Sahin-Tóth (Boston, USA)
Genetics of pancreatitis with a focus on trypsin activation.
14:30 – 15:00 Jonas Rosendahl (Leipzig, Germany)
Genetics of alcoholic and non-alcoholic pancreatitis.
15:00 – 15:30 Federico Canzian (Heidelberg, Germany)
Genetic susceptibility to pancreatic cancer.
COFFEE BREAK
16:00 – 18:00 HPSG meeting
Lajos Tisza Meeting Room
Chairs:Áron Vincze (Pécs, Hungary), Balázs Kui (Szeged), Richard Szmola (Budapest, Hungary)
Session introduction by István Hritz (Budapest, Hungary)
16:00 – 16:10 Péter Hegyi (Szeged, Hungary)
Working rules of HPSG
16:10 – 16:25 István Hritz (Budapest, Hungary)
HPSG Cohort: AP
16:25 – 16:40 Ákos Szűcs (Budapest, Hungary)
HPSG Cohort: CP
16:40 – 16:55 Andrea Párniczky (Budapest, Hungary)
HPSG Cohort: PP
16:55 – 17:10 Zsuzsanna Kahán (Szeged, Hungary)
HPSG Cohort PC
17:10 – 18:00 Prospective studies - Central and Eastern European Working
Groups
Lajos Tisza Meeting Room
Chairs:Ewa Małecka-Panas (Łódź, Poland), Dimitry Bordin (Moscow, Russia), Natalya Gubergrits (Donetsk, Ukraine)
17:10 – 17:30 Péter Hegyi (Szeged, Hungary)
Introducing the International Centres, future perspectives
17:30 – 17:45 István Hritz (Budapest, Hungary)
Introduction of EASY trial
17:45 – 18:00 Fanni Zsoldos (Budapest, Hungary)
Introduction of PINEAPPLE trial
18:00 – 18:15 Andrea Párniczky (Budapest, Hungary)
Introduction of APPLE trial
18:15 – 18:30 Zsolt Dubravcsik (Kecskemét, Hungary)
Introduction of PREPAST trial
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11:30 – 15:00 Paralel meeting for the Hungarian data administrators
(in Hungaran)
Párhuzamos előadás magyar adminisztrátorok részére
István Vedres Meeting Room
11.30 – 12.15 Ebéd
12.15 – 12.45 Szentesi Andrea OPR igazgató (Szeged, Hungary)
OPR és weboldal újdonságok, induló prospektív vizsgálatok
Szünet
13.30 – 15.00 Szentesi Andrea OPR igazgató (Szeged, Hungary)
Új űrlapok bemutatása, feltöltéssel kapcsolatos kérdések
megbeszélése
20:00 Joint Dinner of HPSG and the Faculty of ALPD
Szeged H6720 Roosevelt tér 14 – Fisher’s restaurant
22-23 NOVEMBER 2014 – 9th ALPD symposium
www.alpd2014.hu
22 NOVEMBER 2014 (Saturday)
800 – 810Opening of the 9th ALPD meeting
SESSION 1 : State of the Art Lectures “ Overview on alcohol-induced pancreatic and liver diseases”
810 – 825Alcoholic Liver Disease: Do Genes or Environment Matter More?
Samir Zakhari (USA)
825 – 850Mechanisms by which alcohol predisposes to pancreatitis: an overview
Anna Gukovskaya (USA)
850 – 915Morphogens, metabolic reprogramming, and alcoholic liver disease
Hidekazu Tsukamoto (USA)
SESSION 2 : “Selected oral presentations (1-3)”
915 - 945
945 – 1000Coffee break
SESSION 3 : “Pancreatic and liver cancer development and therapy”
1000 – 1025Pancreatic cancer - the microenvironment needs attention too
Minoti Apte (Australia)
1025 – 1050Cell cycle regulators are key factors in liver pathology
Luis Fajas (France)
1050 – 1115Neddylation and liver cancer: new therapeutical approach
Maria Luz Martinez-Chantar (Spain)
1115 – 1140Ca2+, cAMP and migration of pancreatic cancer cells
Alexei Tepikin (UK)
1140 – 1205Novel therapeutics for pancreatic and liver cancer
Ashok Saluja (USA)
1205 – 1330Lunch and poster viewing
SESSION 4: “The effects of alcohol on Ca2+ signalling and on cellular homeostasis”
1330 – 1355NFAT isoform activation by sub-cellular calcium signals
Anant Parekh (UK)
1355 – 1420Pathological Ca2+ signals, their effects and how to prevent them
Ole Petersen (UK)
1420 – 1445Alcohol, calcium signaling, and secretion in cholangiocytes
Michael Nathanson (USA)
1445 – 1510Acid sphingomyelinase in steatohepatitis
José Carlos Fernández-Checa (Spain)
SESSION 5: “Selected oral presentations (4-6)”
1510 – 1540
1540 – 1600Coffee break
SESSION 6: “Epithelial physiology and the role of epithelial cells in alcohol induced tissue damage”
1600 – 1625Translocation between PI(4,5)P2 microdomains determines STIM1 conformation and gating of Orai1
Shmuel Muallem (USA)
1625 – 1650The role of pancreatic ducts in the pathogenezis of acute pancreatitis
Zoltán Rakonczay Jr. (Hungary)
1650 – 1715Function and repair of dental enamel - potential role of epithelial transport processes of ameloblasts
Gábor Varga (Hungary)
1930 – 2230Welcome reception and dinner
23 NOVEMBER 2014 (Sunday)
SESSION 7: “Genetics of alcohol-related pancreatic diseases”
800 – 825How does alcohol contribute to pancreatic diseases?
David Whitcomb (USA)
825 – 850Genetic clues towards a mechanism of alcoholic chronic pancreatitis
Miklós Sahin-Tóth (USA)
850 – 915Genetic susceptibility factors for alcohol-induced chronic pancreatitis
Marcus Lerch (Germany)
915 – 940Genetic models of pancreatitis: how CF animal models can help us understand the pathogenesis?
Aliye Uc (USA)
SESSION 8: “Selected oral presentations (7-9)”
940 – 1010
1010 – 1025Coffee break
SESSION 9: “Alcohol-induced inflammation and immune response - Liver”
1025 – 1050Metabolic and microbial danger signals in alcoholic liver disease
Gyöngyi Szabó (USA)
1050 – 1115Opposing role of type I vs. type II NKT cells in alcoholic liver disease—implications for novel intervention
Vipin Kumar (USA)
1115 – 1140Cellular and molecular drivers in alcoholic hepatitis
Ramon Bataller (USA)
1140 – 1205Circadian Clock Control of Alcoholic Liver Disease by Nuclear Receptor Signaling
Li Wang (USA)
1205 – 1330Lunch and poster viewing
SESSION 10: “Alcohol-induced inflammation and immune response - Pancreas”
1330 – 1355Stephen Pandol (USA)
1355 – 1420Involvement of Alcohol and Fat in Acute Pancreatitis: a Dangerous Liaison
David Criddle (UK)
1420 – 1445Fat in pancreatitis
Vijay Singh (USA)
SESSION 11: “Alcohol-related mitochondrial dysfunction”
1445 – 1510György Hajnóczky (USA)
1510 – 1535Joannes Hoek (USA)
1535 – 1600The crucial role of mitochondrial damage and consequent breakdown of bioenergetics in acute pancreatitis
Peter Hegyi (Hungary)
1600 – 1615Coffee break
SESSION 12: “Non-alcoholic and alcoholic fatty liver diseases I.”
1615 – 1640Bile acid signalling and non-alcoholic fatty liver disease
Peter Jansen (The Netherlands)
1640– 1705The role of alcohol-induced liver hypoxia
Yatrik Shah (USA)
1705 – 1730The role of the hepatic endocannabinoid system in alcohol-related pathologies
George Kunos (USA)
1730 – 1755NADPH oxidases in alcoholic liver disease
Natalie Torok (USA)
1755 – 1800Closure of the meeting
2000 - 2300Gala dinner, award presentations
End of Programme
Funding for this conference was made possible (in part) by Grant R13AA20691 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices or organizations imply endorsement by the U.S. Government.